Wondering what treatment with VIVITROL is like? You could be someone who has just begun their recovery journey, or someone who has been battling opioid dependence for years. No matter the situation, if living an opioid-free recovery journey is your goal, VIVITROL and counseling may help you stay on track.

Here are a few things to know before and during treatment:


  • Before starting treatment with VIVITROL, talking openly and honestly to a healthcare provider about your treatment goals can help. Need help finding a healthcare provider? The Provider Locator tool may assist you in finding a heathcare provider who can answer your questions about VIVITROL.
  • To be effective, VIVITROL must be used with other drug recovery programs such as counseling.1 VIVITROL may not work for everyone.
  • If you decide to begin treatment with VIVITROL, you will need to be off all opioids for at least 7 to 14 days before your first injection.2
  • This journey may include medically supervised withdrawal (also known as opioid detoxification).1
  • You should not receive VIVITROL if you2:
    • are using or have a physical dependence on opioid-containing medicines or opioid street drugs.
    • are having opioid withdrawal symptoms. Opioid withdrawal symptoms may happen when you have been taking opioid-containing medicines or opioid street drugs regularly and then stop.
    • are allergic to naltrexone or any of the ingredients in VIVITROL or the liquid used to mix VIVITROL (diluent).
  • Once your healthcare provider determines you are ready for the first dose of VIVITROL, they must prepare and administer the injection. VIVITROL must be injected by a healthcare provider. VIVITROL is injected by a healthcare provider, about 1 time each month.2
  • When you receive your first dose, you can set up a follow-up appointment with your healthcare provider and ask for instructions on next steps.
  • If you need help transitioning from an outpatient or other setting, you can ask your healthcare provider about available patient support services.


  • After taking your first dose of VIVITROL, work with your healthcare provider to schedule the next dose in 4 weeks or 1 month. VIVITROL is a once-monthly medication and is always administered by a healthcare provider.2
  • To be effective, VIVITROL must be used with other drug recovery programs such as counseling. If VIVITROL becomes part of your recovery journey, ask your healthcare provider for assistance finding services appropriate to your treatment goals.
  • Always notify your healthcare provider if you2:
    • become pregnant or intend to become pregnant during treatment with VIVITROL
    • are breastfeeding
    • experience respiratory symptoms such as trouble breathing, coughing, or wheezing when taking VIVITROL
    • experience any allergic reactions when taking VIVITROL
    • experience other unusual or significant side effects while on VIVITROL therapy
  • If you have questions during treatment with VIVITROL, don’t hesitate to call your healthcare provider or contact a representative by calling 1-800-VIVITROL (1-800-848-4876).
  • During treatment, you can ask your healthcare provider about Vivitrol2getherSM patient support services to assist you with obtaining and scheduling treatment. Vivitrol2getherSM provides:
    • a Coordinator,* who can help with getting monthly injections as prescribed by your healthcare provider
    • aid in coordinating follow-on care from a residential facility or other settings for your injection
    • VIVITROL® Co-pay Savings Program information on eligibility requirements and enrollment
    • help with arranging appointments and follow-up reminders

*A Coordinator does not provide medical advice or individual patient care. Consult with your healthcare provider for medical questions regarding your care.

VIVITROL is not right for everyone. There are significant risks from VIVITROL treatment, including risk of opioid overdose, severe reaction at the injection site and sudden opioid withdrawal.
See Important Safety Information below. Discuss all benefits and risks with a healthcare provider. See Prescribing Information and Medication Guide.


  1. VIVITROL [prescribing information]. Waltham, MA: Alkermes, Inc; rev March 2021.
  2. VIVITROL [medication guide]. Waltham, MA: Alkermes, Inc; rev May 2020.

*Terms and Conditions

Eligibility for Alkermes-Sponsored Co-pay Savings. This offer is only available to patients 18 years or older, with a prescription consistent with the Prescribing Information and the patient is not enrolled in, or covered by, any local, state, federal or other government program that pays for any portion of medication costs, including but not limited to Medicare, including Medicare Part D or Medicare Advantage plans; Medicaid, including Medicaid Managed Care and Alternative Benefit Plans under the Affordable Care Act; Medigap; VA; DOD; TRICARE; or a residential correctional program.
Additional Terms of Use: This offer is not conditioned on any past, present, or future purchase, including refills. Alkermes reserves the right to rescind, revoke, or amend this offer, program eligibility, and requirements at any time without notice. This offer is limited to one per patient, may not be used with any other offer, is not transferable and may not be sold, purchased or traded, or offered for sale, purchase or trade. Void where prohibited by law. Program Administrator or its designee will have the right upon reasonable prior written notice, during normal business hours, and subject to applicable law, to audit compliance with this program.