Wondering what treatment with VIVITROL is like? You could be someone who has just begun their recovery journey, or someone who has been battling opioid dependence for years. No matter the situation, if living an opioid-free recovery journey is your goal, VIVITROL and counseling may help you stay on track.

Here are a few things to know before and during treatment:


  • Before starting treatment with VIVITROL, talking openly and honestly to a healthcare provider about your treatment goals can help. Need help finding a healthcare provider? The Provider Locator tool may assist you in finding a heathcare provider who can answer your questions about VIVITROL.
  • If you decide to begin treatment with VIVITROL, you will need to be off all opioids for at least 7 to 14 days before your first injection.
  • This journey may include medically supervised withdrawal (also known as opioid detoxification).
  • You should not receive VIVITROL if you2:
    • are using or have a physical dependence on opioid-containing medicines or opioid street drugs.
    • are having opioid withdrawal symptoms. Opioid withdrawal symptoms may happen when you have been taking opioid-containing medicines or opioid street drugs regularly and then stop.
    • are allergic to naltrexone or any of the ingredients in VIVITROL or the liquid used to mix VIVITROL (diluent).
  • Once your healthcare provider determines you are ready for the first dose of VIVITROL, he or she will administer the injection. VIVITROL is injected by a healthcare provider, about 1 time each month.2
  • When you receive your first dose, you can set up a follow-up appointment with your healthcare provider and ask for instructions on next steps.
  • If you need help transitioning from an outpatient or other setting, you can ask your healthcare provider about available patient support services.
  • To be effective, VIVITROL must be used with other drug recovery programs such as counseling.1 If VIVITROL becomes part of your recovery journey, ask your healthcare provider for assistance finding services appropriate to your goals.2


  • After taking your first dose of VIVITROL, work with your healthcare provider to schedule the next dose in 4 weeks or 1 month. VIVITROL is a once-monthly medication and is always administered by a healthcare provider.1
  • During treatment, you can ask your healthcare provider about Vivitrol2getherSM patient support services to assist you with obtaining and scheduling treatment. Vivitrol2getherSM provides:
    • a Nurse Coordinator,* who can help with getting monthly injections as prescribed by your healthcare provider
    • aid in coordinating follow-on care from a residential facility or other settings for your injection
    • VIVITROL® Co-pay Savings Program information on eligibility requirements and enrollment
    • help with arranging appointments and follow-up reminders
  • Always notify your healthcare provider if you:
    • become pregnant or intend to become pregnant during treatment with VIVITROL
    • are breastfeeding
    • experience respiratory symptoms such as trouble breathing, coughing, or wheezing when taking VIVITROL
    • experience any allergic reactions when taking VIVITROL
    • experience other unusual or significant side effects while on VIVITROL therapy
  • If you have questions during treatment with VIVITROL, don’t hesitate to call your healthcare provider or contact a representative by calling 1-800-VIVITROL (1-800-848-4876).

*A Nurse Coordinator does not provide medical advice or individual patient care. Consult with your healthcare provider for medical questions regarding your care.

VIVITROL is not right for everyone. There are significant risks from VIVITROL treatment, including risk of opioid overdose, severe reaction at the injection site and sudden opioid withdrawal.
See Important Safety Information below. Discuss all benefits and risks with a healthcare provider. See Prescribing Information and Medication Guide.


  1. VIVITROL [prescribing information]. Waltham, MA: Alkermes, Inc; rev December 2018.
*Eligibility for Alkermes-Sponsored Co-pay Assistance: Offer valid only for prescriptions for FDA-approved indications. You must be at least 18 years old. If you are purchasing your VIVITROL® prescriptions with benefits from Medicare, including Medicare Part D or Medicare Advantage plans; Medicaid, including Medicaid Managed Care or Alternative Benefit Plans (“ABPs”) under the Affordable Care Act; Medigap; Veterans Administration (“VA”); Department of Defense (“DoD”); TriCare®; or any similar state funded programs such as medical or pharmaceutical assistance programs, you are not eligible for this offer. Void where prohibited by law, taxed or restricted. Subject to plan benefit design requirements. Alkermes, Inc. reserves the right to rescind, revoke or amend these offers without notice.