If you ever need emergency medical treatment, a Pain Management Card lets other doctors and nurses know that you are taking VIVITROL. This card includes information that will help them provide you with the best possible care.


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If you ever need emergency medical treatment, a Pain Management Card lets other doctors and nurses know that you are taking VIVITROL. This card includes information that will help them provide you with the best possible care.
VIVITROL is not right for everyone. There are significant risks from VIVITROL treatment, including risk of opioid overdose, severe reaction at the injection site, sudden opioid withdrawal, liver damage, or hepatitis.
Talk to your healthcare provider about naloxone, a medicine that is available to patients for the emergency treatment of an opioid overdose.
Call 911 or get emergency medical help right away in all cases of known or suspected opioid overdose, even if naloxone is administered.
If you are being treated for alcohol dependence but also use or are addicted to opioid-containing medicines or opioid street drugs, it is important that you tell your healthcare provider before starting VIVITROL to avoid having sudden opioid withdrawal symptoms when you start VIVITROL treatment.
See Important Safety Information.
See Prescribing Information and Medication Guide.
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Risk of opioid overdose. You can accidentally overdose in two ways.
Tell your family and the people closest to you of this increased sensitivity to opioids and the risk of overdose.
Talk to your healthcare provider about naloxone, a medicine that is available to patients for the emergency treatment of an opioid overdose.
Call 911 or get emergency medical help right away in all cases of known or suspected opioid overdose, even if naloxone is administered.
Severe reactions at the site of injection. Some people on VIVITROL have had severe injection site reactions, including tissue death. Some of these reactions have required surgery. VIVITROL must be injected by a healthcare provider. Call your healthcare provider right away if you notice any of the following at any of your injection sites:
Tell your healthcare provider about any reaction at an injection site that concerns you, gets worse over time, or does not get better within two weeks.
Sudden opioid withdrawal. To avoid sudden opioid withdrawal, you must stop taking any type of opioid, including street drugs; prescription pain medicines; cough, cold, or diarrhea medicines that contain opioids; or opioid-dependence treatments, including buprenorphine or methadone, for at least 7 to 14 days before starting VIVITROL. If your doctor decides that you don't need to complete detox first, he or she may give you VIVITROL in a medical facility that can treat sudden opioid withdrawal. Sudden opioid withdrawal can be severe and may require hospitalization.
Liver damage or hepatitis. Naltrexone, the active ingredient in VIVITROL, can cause liver damage or hepatitis. Tell your healthcare provider if you have any of these symptoms during treatment with VIVITROL:
Your healthcare provider may need to stop treating you with VIVITROL if you get signs or symptoms of a serious liver problem.
You must stop taking opioids before you start receiving VIVITROL. To be effective, VIVITROL must be used with other alcohol or drug recovery programs such as counseling. VIVITROL may not work for everyone. It is not known if VIVITROL is safe and effective in children.
Tell your healthcare provider about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your healthcare provider if you take any opioid-containing medicines for pain, cough or colds, or diarrhea.
If you are being treated for alcohol dependence but also use or are addicted to opioid-containing medicines or opioid street drugs, it is important that you tell your healthcare provider before starting VIVITROL to avoid having sudden opioid withdrawal symptoms when you start VIVITROL treatment.
Depressed mood. Sometimes this leads to suicide, or suicidal thoughts, and suicidal behavior. Tell your family members and people closest to you that you are taking VIVITROL.
Pneumonia. Some people receiving VIVITROL treatment have had a type of pneumonia that is caused by an allergic reaction. If this happens to you, you may need to be treated in the hospital.
Serious allergic reactions. Serious allergic reactions can happen during or soon after an injection of VIVITROL. Tell your healthcare provider or get medical help right away if you have any of these symptoms:
These are not all the side effects of VIVITROL. Tell your healthcare provider if you have any side effect that bothers you or that does not go away. You are encouraged to report all side effects to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.
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This Brief Summary is based on the VIVITROL Medication Guide (Rev. March 2021).
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The Provider Locator is compiled and published by Alkermes, Inc. as a reference source of demographic and professional information on individual licensed healthcare providers and healthcare provider entities (hereinafter collectively referred to as healthcare provider) in the United States who have experience in the treatment of alcohol dependence and/or opioid dependence. The Provider Locator is searchable by ZIP code or by city and state. Healthcare providers' enrollment and participation in the Provider Locator is voluntary and free of charge and, along with the provider-specific information in the Provider Locator, is based solely on healthcare provider responses. The Provider Locator is provided by Alkermes for use by the medical and dependence treatment communities, potential patients and/or their families in order to find information on, and locate healthcare providers for the treatment of alcohol dependence or opioid dependence. Alkermes is not responsible for, and the Provider Locator is not intended as a tool for, verifying the credentials, expertise, abilities or quality of care of any healthcare provider included in the Provider Locator. Inclusion in the Provider Locator does not imply referral, recommendation or endorsement nor does omission in the Provider Locator imply Alkermes' disapproval. We recommend that, before scheduling an appointment to see any healthcare provider, you research the credentials of the healthcare provider and satisfy yourself that the healthcare provider provides the quality of care desired. You are prohibited from using, downloading, republishing, selling, duplicating, or "scraping" for commercial or any other purpose whatsoever, the Provider Locator or any of the data listings or other information contained therein, in whole or in part, in any medium whatsoever. The information from the Provider Locator is provided on an "AS-IS" basis. Alkermes disclaims all warranties, either express or implied, including but not limited to the implied warranties of merchantability and fitness for particular purpose. Without limiting the foregoing, Alkermes does not warrant or represent that the Provider Locator or any part thereof is accurate or complete. You assume full responsibility for the communications with any healthcare provider you contact through the Provider Locator. Alkermes shall in no event be liable to you or to anyone for any decision made or action taken by you in the reliance on information.
During the evolving COVID-19 situation, we want to help patients with access to receiving their injection of VIVITROL® (naltrexone for extended-release injectable suspension). If you need access to alternate injection providers, please contact Vivitrol2getherSM Patient Support Services at 1-800-VIVITROL (1-800-848-4876) for assistance in locating a healthcare provider who is providing injections or click on 'Find A Provider' to get a listing of injection providers in your area. Vivitrol2gether can contact injection sites to confirm treatment availability.