If you or someone you know is considering treatment with VIVITROL, you probably have questions. Use these discussion guides to help you and your loved one start conversations with a healthcare provider about a treatment plan that may include VIVITROL.



Healthcare Provider Discussion Guide for Caregivers 1.2MB

Communication can lead to understanding

Patient stories reflect personal experiences. Individual experiences may vary.



  • What is the most important information I should know about VIVITROL?
  • What should I know about the possible side effects?
  • Why do I have to detox from opioids?
  • How will my injections be scheduled?
  • What are my counseling options?
  • Where do I go to get my injections?
  • Can I take opioid-containing medicines while on VIVITROL?
  • Do you have any patients who are on VIVITROL?
  • Am I eligible for the Co-pay Savings Program to help pay for VIVITROL?

Be sure to read and understand the Medication Guide before starting treatment with VIVITROL.


Tell your healthcare provider about all your medical conditions, including if you1:

  • Have liver problems
  • Use or abuse street (illegal) drugs
  • Have hemophilia or other bleeding problems
  • Have kidney problems
  • Have any other medical conditions
  • Are pregnant or plan to become pregnant. It is not known if VIVITROL will harm your unborn baby.
  • Are breastfeeding. It is not known if VIVITROL passes into your milk, and if it can harm your baby. Naltrexone, the active ingredient in VIVITROL, is the same active ingredient in tablets taken by mouth that contain naltrexone. Naltrexone from tablets passes into breast milk. Talk to your doctor about whether you will breastfeed or take VIVITROL. You should not do both.

Tell your healthcare provider about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your healthcare provider if you take any opioid-containing medicines for pain, cough or colds, or diarrhea.

Use the Provider Locator for help locating a healthcare professional in your area who can discuss VIVITROL.


You should not receive VIVITROL if you1:

  • Are using or have a physical dependence on opioid-containing medicines or opioid street drugs.
  • Have opioid withdrawal symptoms. Opioid withdrawal symptoms may happen when you have been taking opioid-containing medicines or opioid street drugs regularly and then stop.
  • Are allergic to naltrexone or any of the ingredients in VIVITROL or the liquid used to mix VIVITROL.

VIVITROL has not been studied in children under the age of 18 years.

VIVITROL is not right for everyone. There are significant risks from VIVITROL treatment, including risk of opioid overdose, severe reaction at the injection site and sudden opioid withdrawal.
See Important Safety Information below. Discuss all benefits and risks with a healthcare provider. See Prescribing Information and Medication Guide.


  1. VIVITROL [medication guide]. Waltham, MA: Alkermes, Inc; rev May 2020.

*Terms and Conditions

Eligibility for Alkermes-Sponsored Co-pay Savings. This offer is only available to patients 18 years or older, with a prescription consistent with the Prescribing Information and the patient is not enrolled in, or covered by, any local, state, federal or other government program that pays for any portion of medication costs, including but not limited to Medicare, including Medicare Part D or Medicare Advantage plans; Medicaid, including Medicaid Managed Care and Alternative Benefit Plans under the Affordable Care Act; Medigap; VA; DOD; TRICARE; or a residential correctional program.
Additional Terms of Use: This offer is not conditioned on any past, present, or future purchase, including refills. Alkermes reserves the right to rescind, revoke, or amend this offer, program eligibility, and requirements at any time without notice. This offer is limited to one per patient, may not be used with any other offer, is not transferable and may not be sold, purchased or traded, or offered for sale, purchase or trade. Void where prohibited by law. Program Administrator or its designee will have the right upon reasonable prior written notice, during normal business hours, and subject to applicable law, to audit compliance with this program.