Opioid dependence

There’s help for you or your loved one with opioid dependence.

The signs and symptoms of opioid dependence may include some or all of the following:

  • A need for an increased amount of opioids to relieve pain or get high
  • Feeling physical or mental withdrawal after stopping opioid use
  • Unsuccessful attempts to cut down or control use
  • Great deal of time spent trying to get more opioids, use opioids or recover from their effects

Not every dependent person will have all of these signs or symptoms, but if you think you or a loved one may be dependent on opioids, consult a healthcare professional.

Opioid dependence is a chronic condition, and remaining opioid-free is a challenge. Relapse can happen even after detoxification. Relapse does not mean failure.

ABOUT VIVITROL® (naltrexone for extended-release injectable suspension):

  • Once-monthly injection
  • Non-addictive — VIVITROL doesn’t lead to physical dependence


  • To help prevent relapse to opioid dependence after detox
  • To treat alcohol dependence. You should stop drinking before starting VIVITROL
  • Before starting VIVITROL, you must be opioid-free for a minimum of 7-14 days to avoid sudden opioid withdrawal
  • Do not take VIVITROL if you have any symptoms of opioid withdrawal
  • VIVITROL must be used with other drug or alcohol recovery programs such as counseling
  • VIVITROL may not work for everyone and has not been studied in children
Learn more

Talk with your healthcare provider to see if VIVITROL might be the right treatment option for you or your loved one. If you don't have a healthcare provider, find one in your area.

VIVITROL is not right for everyone. There are significant risks from VIVITROL treatment, including risk of opioid overdose, severe reaction at the injection site and sudden opioid withdrawal.
See Important Safety Information below. Discuss all benefits and risks with a healthcare provider. See Prescribing Information and Medication Guide.

Find a VIVITROL® treatment provider

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This tool can help you find a healthcare provider in your area who can answer your questions about VIVITROL.

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Learn how the VIVITROL® Co-pay Savings Program may assist eligible* patients with out-of-pocket expenses for their VIVITROL prescriptions.


*Eligibility for Alkermes-Sponsored Co-pay Assistance: Offer valid only for prescriptions for FDA-approved indications. You must be at least 18 years old. If you are purchasing your VIVITROL prescriptions with benefits from Medicare, including Medicare Part D or Medicare Advantage plans; Medicaid, including Medicaid Managed Care or Alternative Benefit Plans (“ABPs”) under the Affordable Care Act; Medigap; Veterans Administration (“VA”); Department of Defense (“DoD”); TriCare®; or any similar state funded programs such as medical or pharmaceutical assistance programs, you are not eligible for this offer. Void where prohibited by law, taxed or restricted. Alkermes, Inc. reserves the right to rescind, revoke, or amend these offers without notice.