Alcohol addiction is a chronic, relapsing brain disease that affects people psychologically and physically. Effective treatment programs can address both aspects of addiction through counseling and medication.1,2 If you are seeking medication as part of your treatment plan, consider VIVITROL. VIVITROL is a non-addictive, once-monthly treatment proven to help reduce heavy drinking days in alcohol dependent patients when used with counseling. VIVITROL and counseling help reinforce recovery for one month at a time while you work on the psychological aspects of addiction through counseling.3
TREATING ALCOHOL DEPENDENCE
WITH VIVITROL AND COUNSELING4,5
When used as part of a treatment plan that includes counseling, VIVITROL can help you reduce heavy-drinking days.
*Heavy drinking was defined as a self-report of 5 or more standard drinks consumed on a given day for male patients and 4 or more drinks for female patients. **Continuous abstinence was defined as no self-reported alcohol use for all weekly visits.
Is there a risk of severe reactions at the injection site with VIVITROL?
Yes. One serious side effect of VIVITROL is severe reactions at the site of the injection, including tissue death. Some injection site reactions have required surgery. Call your healthcare provider right away if you notice any of the following at your injection site:
- Intense pain
- The area feels hard
- An open wound
- A dark scab
Tell your healthcare provider about any injection site reaction that concerns you, gets worse over time, or does not get better by two weeks after the injection.
Is there a risk of sudden opioid withdrawal when starting VIVITROL?
Yes. One serious side effect of VIVITROL is sudden opioid withdrawal. You must stop taking any opioids or opioid-containing medications, including buprenorphine or methadone, for at least 7 to 14 days before starting VIVITROL. If your healthcare provider decides that you don’t need to complete detox first, he or she may give you VIVITROL in a medical facility that can treat sudden opioid withdrawal. Sudden opioid withdrawal can be severe and may require hospitalization.
Can VIVITROL cause liver damage or hepatitis?
Yes. One serious side effect of VIVITROL is liver damage or hepatitis. Naltrexone, the active ingredient in VIVITROL, can cause liver damage or hepatitis. Tell your healthcare provider if you have any of the following symptoms of liver problems during VIVITROL treatment:
- Stomach area pain lasting more than a few days
- Yellowing of the whites of your eyes
- Dark urine
Your healthcare provider may need to stop treating you with VIVITROL if you get signs or symptoms of a serious liver problem.
If my healthcare provider is considering VIVITROL treatment for my alcohol dependence, do I need to tell my healthcare provider that I take opioids?
Yes. If you are being treated for alcohol dependence but also use or are addicted to opioid-containing medicines or opioid street drugs, it is important that you tell your healthcare provider before starting VIVITROL to avoid having sudden opioid withdrawal symptoms when you start VIVITROL treatment. Know the medications you take. Keep a list of them to show your healthcare provider and pharmacist when you get a new medicine.
VIVITROL is not right for everyone. There are significant risks from VIVITROL treatment, including risk of opioid overdose, severe reaction at the injection site and sudden opioid withdrawal.
See Important Safety Information below. Discuss all benefits and risks with a healthcare provider. See Prescribing Information and Medication Guide.