If you or your loved one is considering treatment options for an opioid-free recovery journey, it may be time to discuss VIVITROL with a healthcare provider.
THINGS TO KNOW ABOUT VIVITROL1:
- Opioid blocker
- Administered by a healthcare provider
- Once-monthly injection
- Used with counseling
- Not a narcotic
- Requires opioid detox
Before starting VIVITROL, you must be opioid-free for a minimum of 7 to 14 days to avoid sudden opioid withdrawal.
One Mother's Caregiver Story
Patient stories reflect personal experiences. Individual experiences may vary.
"I think that along with counseling and along with the injection, we'd finally found a treatment that was right for her."
TREATING OPIOID DEPENDENCEWITH VIVITROL AND COUNSELING1,2
When used as part of a treatment plan that includes counseling, VIVITROL prevents relapse to opioid dependence after opioid detox.
VIVITROL AND COUNSELING:PROVEN TO PREVENT RELAPSES
More patients achieved complete abstinence* with VIVITROL and counseling than with placebo1,2
- 45 out of 126 patients treated with VIVITROL had complete abstinence compared to 28 out of 124 patients treated with placebo†
Patients were less likely to relapse to dependence2,3
- Only 1 patient discontinued due to relapse compared to 17 patients on placebo
- 94% fewer relapses to dependence with VIVITROL
Patients had a significant reduction in opioid cravings2
- Patients treated with VIVITROL and counseling experienced a decrease in craving, while patients who received placebo had an increased craving for opioids‡
- Patients treated with VIVITROL experienced an average decrease in craving score of 10.1 from 18.2
- Patients treated with placebo experienced an average increase in craving score of 0.7 from 21.8
This data is from a 6-month, double-blind, placebo-controlled, randomized clinical study of 124 opioid-dependent patients treated with placebo and counseling who were compared to 126 opioid-dependent patients treated with VIVITROL and counseling, following opioid detoxification.1,2
*Complete abstinence was defined as a negative urine drug test for opioids and no self-reported opioid use for all weekly visits. †During Weeks 5-24 of the study. Data were not collected during Weeks 1-4 of the trial to allow for stabilization of abstinence. ‡Craving described as a "need for opioids" and measured on a scale from 0-100 (with 0 being "none" and 100 being "very much so") was reported every week.WHAT DOES VIVITROL DO? SEE HOW IT WORKS.
Is there a risk of opioid overdose with VIVITROL?4
Yes. One serious side effect of VIVITROL is the risk of opioid overdose. Using opioids, even in amounts that you used before VIVITROL treatment, can lead to accidental overdose, serious injury, coma, or death.
- Do not take large amounts of opioids to try to overcome the opioid-blocking effects of VIVITROL.
- Do not use opioids in amounts that you used before VIVITROL treatment. You may even be more sensitive to lower amounts of opioids:
- After detox
- When your next VIVITROL dose is due
- If you miss a dose of VIVITROL
- After you stop VIVITROL treatment
Get emergency medical help right away if you:
- have trouble breathing
- become very drowsy with slowed breathing
- have slow, shallow breathing (little chest movement with breathing)
- feel faint, very dizzy, confused, or have other unusual symptoms.
It is important that you tell your family and the people closest to you of this increased sensitivity to opioids and the risk of overdose.
Is there a risk of severe reactions at the injection site with VIVITROL?4
Yes. One serious side effect of VIVITROL is severe reactions at the site of the injection, including tissue death. Some injection site reactions have required surgery. VIVITROL must be injected by a healthcare provider. Call your healthcare provider right away if you notice any of the following at your injection site:
- Intense pain
- The area feels hard
- Large area of swelling
- An open wound
- A dark scab
Tell your healthcare provider about any injection site reaction that concerns you, gets worse over time, or does not get better by two weeks after the injection.
Is there a risk of sudden opioid withdrawal when starting VIVITROL?4
Yes. One serious side effect of VIVITROL is sudden opioid withdrawal. You must stop taking any opioids or opioid-containing medications, including buprenorphine or methadone, for at least 7 to 14 days before starting VIVITROL. If your healthcare provider decides that you don’t need to complete detox first, he or she may give you VIVITROL in a medical facility that can treat sudden opioid withdrawal. Sudden opioid withdrawal can be severe and may require hospitalization.
VIVITROL is not right for everyone. There are significant risks from VIVITROL treatment, including risk of opioid overdose, severe reaction at the injection site and sudden opioid withdrawal.
See Important Safety Information below. Discuss all benefits and risks with a healthcare provider. See Prescribing Information and Medication Guide.